By Gerald Litwack (Eds.)
Steroids is a thematic quantity from the vintage educational Press sequence, Vitamins and Hormones . Gerald Litwack, the hot editor of this prestigious serial, brings jointly prime individuals to the examine of steroids. those structurally and functionally advanced molecules are of curiosity to a extensive cross-section of endocrinologist, phone biologists, and biochemists. reports comprise reports of constitution, functionality, and law of steroid construction and motion. hence, Vitamins and Hormones keeps to post state-of-the-art reports of curiosity to endocrinologists and biochemists. Others will more and more flip to this carrying on with sequence for complete experiences via major researchers during this and comparable disciplines.
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Extra info for Advances in Research and Applications: Steroids
SCHWABE, AND LEONARD P. FREEDMAN response element. Gln at this position could not reach the base. Arg50 interacts with a DNA phosphate and is buttressed in this interaction by a hydrogen bond with Asp6, a residue that is absolutely conserved in the corresponding position throughout the superfamily. Substitution of the Arg with Gln would allow one but not both of these interactions to be made. Arg57 forms a phosphate backbone contact, and a Gln side chain here would not be sufficiently long to duplicate this interaction.
Endocrinol. 5, 1815-1826. Freedman, L. , Luisi, B. , Korszun, Z. , Sigler, P. , and Yamamoto, K. R. The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain. Nature (London) 334,543-546. Freedman, L. P,, Yamamoto, K. , Luisi, B. , and Sigler, P. J. More fingers in hand. ) 64,444. Freedman, L. , Yoshinaga, S. , and Yamamoto, K. R. In vitro 42 BEN F. LUISI, JOHN W. R. FREEDMAN transcriptional enhancement by purified glucocorticoid receptor derivatives.
65, 145-156. , Yu, V. , Rosenfeld, M. , and Glass, C. K. Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Den 7, 1423-1435. LaBaer, J. D. Thesis, University of California, San Francisco. Landschulz, W. , Johnson, P. , McKnight, S. L. The leucine zipper: A hypothetical structure common to a new class of DNA binding proteins. Science 240, 1759-1764. , and Stehelin, D. Evolution of the nuclear receptor gene superfamily.
Advances in Research and Applications: Steroids by Gerald Litwack (Eds.)